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Representative <t>intracranial</t> pressure <t>(ICP)</t> waveforms in control, sham, and SAH groups. Waveforms are displayed in mmH₂O units and annotated with corresponding mean ± SD values derived from experimental data. Control and sham groups at day 1 demonstrated normal cardiac-synchronous pulsations (~99.0 ± 8.3 units). SAH animals exhibited markedly reduced amplitude on day 1 (~45.0 ± 4.9 units). By day 7, SAH animals showed partial recovery (~64.0 ± 1.5 units), though amplitudes remained lower than control and sham values at the same time point (~83 units).
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Representative <t>intracranial</t> pressure <t>(ICP)</t> waveforms in control, sham, and SAH groups. Waveforms are displayed in mmH₂O units and annotated with corresponding mean ± SD values derived from experimental data. Control and sham groups at day 1 demonstrated normal cardiac-synchronous pulsations (~99.0 ± 8.3 units). SAH animals exhibited markedly reduced amplitude on day 1 (~45.0 ± 4.9 units). By day 7, SAH animals showed partial recovery (~64.0 ± 1.5 units), though amplitudes remained lower than control and sham values at the same time point (~83 units).
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Representative intracranial pressure (ICP) waveforms in control, sham, and SAH groups. Waveforms are displayed in mmH₂O units and annotated with corresponding mean ± SD values derived from experimental data. Control and sham groups at day 1 demonstrated normal cardiac-synchronous pulsations (~99.0 ± 8.3 units). SAH animals exhibited markedly reduced amplitude on day 1 (~45.0 ± 4.9 units). By day 7, SAH animals showed partial recovery (~64.0 ± 1.5 units), though amplitudes remained lower than control and sham values at the same time point (~83 units).

Journal: Frontiers in Neurology

Article Title: Posterior communicating artery vasospasm impairs cerebral pulsatility in an experimental subarachnoid hemorrhage model

doi: 10.3389/fneur.2025.1649577

Figure Lengend Snippet: Representative intracranial pressure (ICP) waveforms in control, sham, and SAH groups. Waveforms are displayed in mmH₂O units and annotated with corresponding mean ± SD values derived from experimental data. Control and sham groups at day 1 demonstrated normal cardiac-synchronous pulsations (~99.0 ± 8.3 units). SAH animals exhibited markedly reduced amplitude on day 1 (~45.0 ± 4.9 units). By day 7, SAH animals showed partial recovery (~64.0 ± 1.5 units), though amplitudes remained lower than control and sham values at the same time point (~83 units).

Article Snippet: Under general anesthesia, a small burr hole was created in the right parietal bone, and a Codman ® intracranial pressure (ICP) microsensor probe (Johnson & Johnson, Codman Division, Randolph, MA, United States) was placed epidurally or in the subdural space adjacent to the cortex.

Techniques: Control, Derivative Assay